Healio (6/20, Mahoney) reported a study found that “adults with treatment-resistant depression who received IV ketamine showed improvement in sadness-related symptoms immediately and in suicidal ideation 3 weeks later.” Researchers observed that “compared with the control group, 24 hours after infusion the intervention group experienced the greatest effects of ketamine on apparent and reported sadness. The researchers also found significant differences between the groups at 24 hours in pessimistic thoughts, inability to feel, concentration difficulties, lassitude and reduced sleep.” In addition, they “found that improvements in sadness and lassitude persisted to day 5 and improvement in apparent sadness lasted to day 12.” Further, researchers “did not observe any significant differences in effect for individual symptoms between the control and intervention groups except for suicidal thoughts only on day 21.” The study was published in The British Journal of Psychiatry. (SOURCE: APA Headlines)