Neurology Advisor (11/18, Saha) reports a study found that “individuals with Alzheimer disease (AD) who also have depression, anxiety, or post-traumatic stress disorder (PTSD) experience symptom onset several years earlier than those without psychiatric comorbidities.” Researchers observed that among study participants diagnosed with probable AD, “43.3% of patients had a history of depression, 32.3% had anxiety, and 1.0% had PTSD. Patients with these conditions experienced AD onset 2.2 years earlier (depression), 3.0 years earlier (anxiety), and 6.8 years earlier (PTSD) than those without them. A clear dose-response relationship was observed, in which having 1 psychiatric condition reduced the age at onset by 1.5 years, 2 conditions by 3.3 years, and 3 or more by 7.7 years.” A second cohort of participants from the National Alzheimer’s Coordinating Center (NACC) “reinforced these results. Participants with depression or anxiety developed AD 2.1 years earlier than those without either condition.” The study was published in Alzheimer’s & Dementia. (SOURCE: APA Headlines)