MedPage Today (9/9, George) reports a study found that “brain iron measured with quantitative susceptibility mapping (QSM) MRI predicted cognitive decline in healthy adults.” Researchers observed that in “158 cognitively unimpaired older adults, higher baseline magnetic susceptibility in the entorhinal cortex was tied to an increased risk of subsequent mild cognitive impairment,” while a “similar association was found in the putamen.” Furthermore, “in a subset of 110 participants with amyloid PET measurements, the relationship between increased magnetic susceptibility and the onset of mild cognitive impairment was even stronger in the entorhinal cortex and putamen.” Researchers concluded that “higher baseline entorhinal cortex and putamen susceptibility in the PET subgroup was also associated with greater global cognitive decline, especially in people with amyloid pathologic abnormalities.” The study was published in Radiology. (SOURCE: APA Headlines)