Healio (1/4, Herpen) reports, “Esmethadone produced fast and consistent positive outcomes in patients for whom previous treatments for depression were not effective,” investigators concluded after conducting a 62-patient, “weeklong phase 2 multicenter randomized, double-blind, placebo-controlled trial, comprising three segments, to assess the effects of two different dosages of esmethadone.” The findings of the “randomized, double-blind study” were published online Dec. 22 in the American Journal of Psychiatry, a publication of the American Psychiatric Association. (SOURCE: APA Headlines)