The New York Times (11/28, Belluck) reported that a “recently recognized form of dementia” known as LATE is “changing the understanding of cognitive decline, improving the ability to diagnose patients and underscoring the need for a wider array of treatments.” On its own, researchers say that “LATE, shorthand for Limbic-predominant age-related TDP-43 encephalopathy, is usually less severe than Alzheimer’s and unfolds more slowly.” The condition is “now estimated to affect about a third of people 85 and older and 10 percent of those 65 and older, according to” guidelines published earlier this year. LATE started to be recognized after about 35 Alzheimer’s researchers convened “from around the world in 2018 to explore designating a new non-Alzheimer’s diagnosis, evaluating data from brain autopsies and other research.” Although there is “no specific treatment for LATE,” the first clinical trial testing nicorandil as “a treatment for LATE is underway at the University of Kentucky.” (SOURCE: APA Headlines)