MedPage Today (3/5, Hlavinka) reports that “two studies examining whether interventions centered on diet and lifestyle can improve depression had mixed results.” In one study, published in JAMA, researchers found that “neither an intervention geared at improving dietary behaviors and promoting a Mediterranean diet (‘food-related behavioral activation therapy’) nor one involving a multinutrient supplement reduced the onset of major depressive disorders.” However, in the other study, also published in JAMA, “patients undergoing a behavioral weight loss intervention involving calorie reduction, physical exercise, and lifestyle videos combined with a problem-solving therapy and as-needed antidepressants did significantly reduce depression.” In an accompanying editorial, “Michael Berk, MD, PhD, and Felice Jacka, PhD, both of Deakin University, in Victoria, Australia,” wrote that the two studies are part of a growing number with positive results, but most previous studies did not involve clinically depressed patients. (SOURCE: APA Headlines)